Comparison of Impact of High versus Low FODMAPs diet on Gut Flora in Patients with Irritable Bowel Syndrome

Afra Wasama Islam, Harsahaj Singh Wilkhoo

Abstract


FODMAPs diet abbreviated for fermentable, oligosaccharides, disaccharides, monosaccharides and polyols significantly influence the gut microbiota. Low FODMAPs diet reduces the intake of fermentable molecule and thus alleviate the symptoms of IBS. This happens because of decreasing gut dysbiosis and visceral hypersensitivity. On the other hand, high FODMAPs diet exacerbates GI symptoms by promoting dysbiosis and increasing harmful short chain fatty acids. Population of firmicutes, Bacteroidetes and Actinobacteria plays a crucial role in development of IBS. Factors such as age, sex, ethnicity and diet influence gut microbiota and symptom severity. IBS patients have a lower composition of beneficial bacteria like bifidobacterium and lactobacillus and increased population of the harmful ones like Enterobacter. Current clinical evidence supports the efficacy of low FODMAPs diet in improving IBS symptoms and altering gut microbiota composition with patients having a better quality of life because of reduced GI symptoms. However, the diet alters the gut environment, and the effect of its long-term impact needs further research. Future studies should also aim on studying personalized dietary intervention for a precise IBS management in patients. Overall, low FODMAPs diet shows promise as therapeutic approach for IBS by providing a better quality of life and symptom reduction.


Keywords


High FODMAPs, Low FODMAPs, Irritable Bowel Syndrome, Gut Microbiota, Gut Dysbiosis, Lifestyle Medicine, Gastroenterology

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References


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DOI: http://dx.doi.org/10.52155/ijpsat.v45.2.6429

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