Clinical Presentation, Diagnosis And Differential Diagnosis Of Pandas Syndrome In Children: Review

Mukhtorjonova Khusnigul Nodirbekovna, Elmurodova Zarina Aslanovna, Matkarimova Dilnoza Doniyorovna

Abstract


In recent years, an assumption has been made about the connection of various choreiform hyperkinesis, tics, myoclonus, and neurosis-like obsessive states in children with β-hemolytic streptococcus group A (BHSA). Currently, early diagnosis of a number of autoimmune diseases, including those caused by β-hemolytic streptococcus group A and the development of differential diagnostic criteria for PANDAS syndrome, as well as the choice of treatment tactics and the prevention of complications in this pathology, is very relevant. PANDAS syndrome, in contrast to minor chorea, is characterized by local, easily stopped tics, with debut disease from 5 years to 12 years. The developed differential diagnostic criteria and the algorithm for the diagnosis of PANDAS syndrome will allow timely diagnosis and application of the necessary treatment tactics.


Keywords


PANDAS syndrome, disease, children, β-hemolytic streptococcus group A

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References


American Psychiatric Association. Diagnostic and statistical manual of mental disorders 4lh ed. — Washington (DC): American Psychiatric Association, 1994.

Castillo, M.L. Sydenham's chorea: MRI and proton spectroscopy / M. Castillo, L. Kwock, A. Arbelaez // Neuroradiology. — 1999. — Vol. 41. — P. 943—945.

Church, A.J. et al. Anti-basal ganglia antibodies in acute and persistent Sydenham's chorea // Neurology. — 2002 (2 of 2). — P. 227—231.

Dale, R.C. Autoimmunity and the basal ganglia: new insights into old diseases // J. Med. — 2003. — Vol. 96. — P. 183—191.

Еареп, V. Adult-Onset tic disorders / V. Eapen, A.J. Lees et al. // Movement Disorders. — 2002. — Vol. 17, № 4. — P. 735—740. - 35)

Fedoseeva, I. The content of noradrenaline in blood serum in children with tic disorders / I. Fedoseeva, T. Poponnikova, L. Galaganova // EuropranJornel of Neurology. – 2010. – Vol. 17, suppl. 3. – P. 520.

Fernandez-Alvarez E. Transient movement disorders in children / J. Neurol. — 1998. — Vol. 245. — P. 1—5.

Harvey S., Singer Serial Immune Markers Do Not Correlate With Clinical Exacerbations in Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections // Pediatrics. – 2008. – vol.121(1). – P.198-1205.

Jancovic, J. Tics and Tourette's Syndrome / In: [E. Tolosa, W.C.Coller, O.S.Gershanik (Eds)] Differential Diagnosis and treatment of movement disorders. — Butterworth- Heinemann,1998. — P. 99—107.

Kofman O. Paroxysmal sneezing. Can Med Assос J 1964;91(11):618.

Kurlan, R. Handbook of Tourette's Syndrome and Related Tic and Behavioral Disorders (Neurological Disease and Therapy). — 2005. — P. 325—329.

Macerollo A., Martino D. Pediatric аutoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an evolving concept. Tremor Other HyperkinetMov (NY). 2013.

Murphy M.L., Pichichero M.E. Prospective identification and treatment of children with pediatric autoimmune neuropsychiatric disorder associated with group A streptococcal infection (PANDAS). Arch PediatrAdolesc Med 2002;156(4):356–61.

Perlmutter S.J., Leitman S.F., Garvey M.A. et al. Therapeutic plasma exchange and intravenous immunoglobulin for obsessive- compulsive disorder and tic disorders in childhood. Lancet 1999;354(9185):1153–8.

Pringsheim, Т., Davenport W.J. , Lang A. // Tics Current Opinion in Neurology. — 2003. — Vol.16. — P. 523—527.

Rampello L. Tic disorders: from pathophysiology to treatment / L. Rampello, A..Alvano, G. Battaglia et al. // J. Neurol. — 2006.— Vol. 253, —P. 1—15.

Roger Kurlan et al. Streptococcal Infection and Exacerbations of Childhood Tics and Obsessive-Compulsive Symptoms: A Prospective Blinded Cohort Study. Pediatrics 2008;121;1188-1197.

Sanchez-Carpintero, R. A preliminary study of the frequency of anti-basal ganglia antibodies and streptococcal infection in attention deficit/hyperactivity




DOI: http://dx.doi.org/10.52155/ijpsat.v27.1.3214

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