C reactive protein, Procalcitonin, Ferritin Levels in Mild, Severe and Critically Ill Patients with Coronavirus Disease 2019 (COVID-19)

Levan Ratiani, Luiza Gabunia, Shorena Khetsuriani, Natia Gamkrelidze, Nino Gogokhia, Teimuraz Makharadze, Elena Varazi, Natia Antia, Nodar Sulashvili

Abstract


The severe acute respiratory syndrome coronavirus-2 has infected millions of people worldwide, causing the COVID-19 pandemic. The pathogenic mechanism of infection is still under investigation.

Due to lack of appropriate treatment, it is important to determine specific biomarkers to help clinicians identify patients at high risk of death, especially among those with severe COVID-19. These inflammatory factors may be prognostic biomarkers for predicting severe COVID-19 infection, therefore early identification of patients with COVID-19 with possible adverse prognostic factors is important for treatment and limiting severe outcomes and death.In the study we investigated the potential interdependence of some laboratory parameters - C reactive protein, procalcitonin, ferritin in different clinical severity COVID‐19 patients. Study results indicate that average values of these biomarkers vary in accordance with severity of COVID-19 infection. These values are explicitly higher in critically ill patients in comparison with mild and severe forms of disease.

Keywords


severe acute respiratory syndrome coronavirus-2, procalcitonin, C-reactive protein, ferritin.

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References


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DOI: http://dx.doi.org/10.52155/ijpsat.v26.2.3096

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Copyright (c) 2021 Levan Ratiani, Luiza Gabunia, Shorena Khetsuriani, Natia Gamkrelidze, Nino Gogokhia, Teimuraz Makharadze, Elena Varazi, Natia Antia, Nodar Sulashvili

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