Epidemiology, Pathogenesis and Treatment of Ulcerative Colitis in South Asia

Umesh Jayarajah, N M M Navarathne, Nandadeva Samarasekera, Nishanthan Subramaniam, Ishan M de Zoysa, Suranjith L Seneviratne

Abstract


Ulcerative colitis (UC) is a chronic inflammatory disorder of the colon and rectum. Its prevalence is on the rise in many non-Western countries and several factors such as changes in lifestyle and improvements in hygiene may account for this. The cultural and ethnic background of South Asia is different from Western countries and other parts of Asia. We have reviewed the scientific literature on UC in South Asia and describe its epidemiology, clinical characteristics, molecular mechanisms, diagnosis and treatment. 


Keywords


Ulcerative colitis, South Asia, Inflammatory bowel disease, genetics, pathogenesis

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DOI: http://dx.doi.org/10.52155/ijpsat.v6.1.222

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Copyright (c) 2017 Umesh Jayarajah, N M M Navarathne, Nandadeva Samarasekera, Nishantahn Subramaniam, Ishan M de Zoysa, Suranjith L Seneviratne

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