Vaping’s Silent Epidemic: Reproductive Harm and Misleading Safety Claims
Abstract
Vaping, which has received considerable encouragement as a better choice than smoking, has gained popularity amongst the younger demographic as well as those individuals who wish to quit smoking. In this paper, we reviewed the literature available on the composition of e-liquids which revealed propylene glycol, glycerin, nicotine, formaldehyde, cadmium, volatile organic compounds, polycyclic aromatic hydrocarbons and a number of other hazardous substances as the primary components. These substances, when inhaled through vaping have proven to negatively impact the reproductive systems of both men and women. While vaping lowers sperm quality and may affect erectile function in men, it has shown to disturb ovarian function, hormone balance, and fertility in women. It has even more disastrous effects on pregnant individuals causing complications like placental malfunction, premature births, and problems with fetal growth. Furthermore, adolescents who metabolize nicotine more rapidly than adults are more susceptible to addiction and may, in the near future, experience disastrous long-term effects. This study solicits the need for more research to eliminate misunderstandings about vaping's safety and emphasizes the need for increased awareness of its detrimental impacts, particularly in relation to reproductive health.
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E. Bonner et al. The chemistry and toxicology of vaping. Pharmacology &
Therapeutics. 2021; 225
Tanya S., Courtney R. Green, Jocelynn L. Cook. Vaping during Pregnancy: What
Are the Potential Health Outcomes and Perceptions Pregnant Women Have?.
Journal of Obstetrics and Gynecology Canada. 2021; 43(2): 219-226.
Gerard Li et al. Replacing smoking with vaping during pregnancy: Impacts on
metabolic health in mice. Reproductive Toxicology. 2020; 96: 293-299.
A. Shruti et al. E-cigarette use in reproductive-aged women and pregnancy: a
rising health concern. Fertility and Sterility. June 2020; 113(6): 1133-1134.
Szumilas K, Szumilas P, Grzywacz A, Wilk A. The Effects of E-Cigarette Vapour
Components on the Morphology and Function of the Male and Female
Reproductive Systems: A Systematic Review. International Journal of
Environmental Research and Public Health. 2020; 17(17): 6152.
Montjean D, Godin Pagé M-H, Bélanger M-C, Benkhalifa M, Miron P. An
Overview of E-Cigarette Impact on Reproductive Health. Life. 2023; 13(3):827.
Choucair B. E-cigarette. Characteristics, safety issues, & regulation.
Encyclopedia Britannica. 2024.
Fadus MC, Smith TT, Squeglia LM. The rise of e-cigarettes, pod mod devices,
and JUUL among youth: Factors influencing use, health implications, and
downstream effects. Drug and Alcohol Dependence. 2019 May 23;201:85–93.
Jones K, Salzman GA. The Vaping Epidemic in Adolescents. 2020.
Australia TI. Greenhalgh, EM. Scollo, MM |Winstanley, MH. 2021.
Goriounova NA, Mansvelder HD. Short- and Long-Term Consequences of
Nicotine Exposure during Adolescence for Prefrontal Cortex Neuronal Network
Function. Cold Spring Harbor Perspectives in Medicine. 2012 Sep
;2(12):a012120.
Yuan M, Cross SJ, Loughlin SE, Leslie FM. Nicotine and the adolescent brain.
The Journal of Physiology. 2015 May 27;593(16):3397–412.
Society E. Vaping may harm fertility in young women. Endocrine Society. 2019
Nov 21.
Your Fertility - Facts About Fertility & How To Improve Your Chance. Your Fertility.
Cousin O, Vandecandelaere A, Bosquet D, Lefranc E, Scheffler F, Copin H, et al.
Cigarette électronique et fertilité : vrais ou faux amis ? Gynécologie Obstétrique
Fertilité & Sénologie. 2023 Mar 15;51(7–8):378–83.
The impact of e-cigarettes smoking on the male reproductive system and
spermatogenesis. PubMed. 2024.
Abud HN. Article Review: Effect of Electronic Cigarettes on Fertility in Male.
Journal for Research in Applied Sciences and Biotechnology. 2024 Mar
;3(1):214–25.
Pincus J, Sandoval V, Dick B, Sanekommu G, Rajasekaran R, Ramasamy R, et
al. E-Cigarette-Associated Endothelial Damage: A Potential Mechanism for
Erectile Dysfunction. Sexual Medicine Reviews. 2021 Apr 27;10(1):168–73.
Ruszkiewicz JA, Zhang Z, Gonçalves FM, Tizabi Y, Zelikoff JT, Aschner M.
Neurotoxicity of e-cigarettes. Food and Chemical Toxicology. 2020 Mar
;138:111245.
Mescolo F, Ferrante G, La Grutta S. Effects of E-Cigarette Exposure on Prenatal
Life and Childhood Respiratory Health: A Review of Current Evidence. Frontiers
in Pediatrics. 2021 Aug 20;9.
Whittington JR, Simmons PM, Phillips AM, Gammill SK, Cen R, Magann EF, et
al. The Use of Electronic Cigarettes in Pregnancy: A Review of the Literature.
Obstetrical & Gynecological Survey. 2018 Sep 1;73(9):544–9.
Orzabal MR, Naik VD, Lee J, Hillhouse AE, Brashear WA, Threadgill DW, et al.
Impact of E-cig aerosol vaping on fetal and neonatal respiratory development
and function. Translational Research. 2022 Mar 26;246:102–14.
Collaco JM, McGrath‐Morrow SA. Developmental Effects of Electronic Cigarette
Use. Comprehensive Physiology. 2022 Mar 29;3337–46.
Orzabal MR, Naik VD, Lee J, Wu G, Ramadoss J. Impact of gestational
electronic cigarette vaping on amino acid signature profile in the pregnant mother
and the fetus. Metabolism Open. 2021 Jul 16;11:100107.
Potter NA, Arita Y, Peltier MR, Zelikoff JT. Ex vivo toxicity of E-cigarette
constituents on human placental tissues. Journal of Reproductive Immunology.
Aug 30;154:103737.
DOI: http://dx.doi.org/10.52155/ijpsat.v48.1.6849
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