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Updates of Role of Stem Cells in Cancer Therapy
Abstract
Stem cell- based treatments show significant remedial potential for treating different human diseases, including cancer. Among the cell types that can be utilized for this reason, mesenchymal stem cells (MSCs) are considered as promising source of stem cells in customized cell-based treatments. The innate tumour-tropic property of MSCs can be utilized to target cancer cells. Albeit the effects of MSCs on cancer progression stay tricky, they have been genetically adjusted or designed as targeted anticancer agents which could hinder tumour growth by impeding various processes of cancer. Also, there are close interactions among MSCs and cancer stem cells (CSCs). MSCs can direct the growth of CSCs through paracrine mechanisms. This review aims to focus on the current information’s about MSCs-based tumour treatments, the opportunities and difficulties, as well as the forthcoming of its further clinical implications.
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DOI: http://dx.doi.org/10.52155/ijpsat.v34.1.4557
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