Carcinome basocellulaire pigmenté: à propos d’un cas malagasy. Pigmented basal cell carcinoma : malagasy case report.

Abstract

Basal cell carcinoma (BCC) constitutes about 70 % of human skin cancer. This malignant neoplasia is characterized by the presence intercellular junction. BCC develop predominantly in fair-skinned human. Pigmented BCC is one of its rare form in subject with fair skin. We report a case of pigmented BCC in Malagasy patient.

A 70 years-old woman, phototype IV, presented to us with pigmented, and painless lesion of the right nasolabial fold, appears 3 years before. She observed an increasing size of lesion after recent manipulation of the lesion. Ulceration occurred and alerted the patient. In clinical examination, we found a non-inflammatory, and brown ulceration which measured 1 cm x 0.4 cm. It was a no oozing ulceration, and there was no bleeding to the touch. We felt skin induration in its basis, which exceeded 0,5cm along the ulceration’s limit. Biopsy exeresis was made with a 0,5cm carcinological margins on all sides of lesion, and brought back operative piece which measured 2.2 x 1 x 0.3cm. Histopathologic examination showed a tumor proliferation in the outer layers of the epidermis, made up of confluent islets cells consisting of epithelial cells, moderately atypical, assuming a palisaded arrangement at their periphery. Melanin deposits were seen within tumor nodules, and gave the diagnosis of pigmented BCC with a complete exeresis.

BCC mainly affects subject with light skin, at whose a BCC is rarely pigmented. For black skinned people, pigmented BCC is not exceptional.