Prevalence And Antibiotic Resistance Pattern Of Staphylococcus Aureus Isolated From Skin Infections

Entesar Emrage, Maha Ali, Mahmoud Saleh, Mohamed Gamal Salah


The aim of this study was to determine antimicrobial resistance profiles of Staphylococcus aureus isolates from skin infections. Out of 280 skin infection specimens, 96 (34.28%) S. aureus strains were isolated and identified. The antimicrobial resistance of 96 isolates was tested with a disc diffusion method. Almost half (47%) isolates were methicillin-sensitive Staphylococcus aureus (MSSA) while 53% were methicillin-resistant Staphylococcus aureus (MRSA). All strains were found to be susceptible to vancomycin while almost all (99%) isolates were resistant to penicillin. Results revealed that 80, 67 and 66% of the investigated isolates were resistant to tetracycline, ciprofloxacin and erythromycin, respectively, while only 16 and 19% of the isolates were resistant to amikacin and gentamicin, respectively


Antibiotic resistance; Staphylococcus aureus; skin infections

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S. DL et al., “Practice guidelines for the diagnosis and management of skin and soft-tissue infections,” Clin. Infect. Dis., vol. 41, no. 10, pp. 1373–1406, Nov. 2005, doi: 10.1086/497143.

A. Ebrahimi, M. Ghasemi, and B. Ghasemi, “Some Virulence Factors of Staphylococci Isolated From Wound and Skin Infections in Shahrekord, IR Iran,” Jundishapur J. Microbiol., vol. 7, no. 4, p. 9225, 2014, doi: 10.5812/JJM.9225.

S. Lakhundi and K. Zhang, “Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology,” Clin. Microbiol. Rev., vol. 31, no. 4, pp. 1–103, Oct. 2018, doi: 10.1128/CMR.00020-18.

H. F. Chambers and F. R. DeLeo, “Waves of resistance: Staphylococcus aureus in the antibiotic era,” Nature Reviews Microbiology, vol. 7, no. 9. pp. 629–641, 2009, doi: 10.1038/nrmicro2200.

B. Aslam et al., “Antibiotic resistance: a rundown of a global crisis,” Infection and Drug Resistance, vol. 11. Dove Medical Press Ltd., pp. 1645–1658, 2018, doi: 10.2147/IDR.S173867.

H. M. Naimi, H. Rasekh, A. Z. Noori, and M. A. Bahaduri, “Determination of antimicrobial susceptibility patterns in Staphylococcus aureus strains recovered from patients at two main health facilities in Kabul, Afghanistan,” BMC Infect. Dis. 2017 171, vol. 17, no. 1, pp. 1–7, Nov. 2017, doi: 10.1186/S12879-017-2844-4.



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