Email this article 
Troubles Electrolytiques chez les Patients Atteints de Diabète Vivant à Bamako, Mali
Abstract
Résumé - Les patients diabétiques développent fréquemment une constellation de troubles électrolytiques qui contribue aux complications observées chez ces malades. L'objectif de cette étude était d'évaluer les perturbations des électrolytes chez les patients diabétiques vivant à Bamako. Le glucose sérique et les électrolytes (Na+, K+ et Cl-) ont été déterminés chez 179 sujets diabétiques et 101 sujets non diabétiques. Tous les patients diabétiques ont présenté une augmentation significative (p-value <0,05) du taux sérique en sodium et potassium. Il a été noté une diminution significative du taux sérique des ions chlorures chez les diabétiques (p-value <0,05). Ainsi, cette étude montre que les patients atteints de diabète sont plus enclins à développer des déséquilibres électrolytiques.
Mots clés: Diabète, Ionogramme sanguin, Hypochlorémie, Hypernatrémie, Hyperkaliémie
Abstract – Diabetic patients frequently develop a constellation of electrolyte disorders that contribute to the complications observed in these patients. The objective of this study was to evaluate electrolyte disturbances in diabetic patients living in Bamako. Serum glucose and electrolytes (Na+, K+ and Cl-) were determined in 179 diabetic and 101 non-diabetic subjects. All diabetic patients showed a significant increase (p-value <0.05) in serum sodium and potassium. There was a significant decrease in serum chloride ion levels in diabetic patients (p-value <0.05). Thus, this study shows that diabetic patients are more prone to develop electrolyte imbalances.
Keywords – Diabetes, Blood Ionogram, Hypochloremia, Hypernatremia, Hyperkalemia
Keywords
Full Text:
PDFReferences
Khanduker S., Ahmed R., Khondker F., Aharama A., Afrose N., Chowdhury MAA. 2017. Electrolyte disturbances in patients with diabetes mellitus. Bangladesh J Med Biochem. 10(1): 27-35.
Diop SN et Diédhiou D. 2015. Le diabète sucré en Afrique sub-saharienne : aspects épidémiologiques et socioéconomiques. Médecine des maladies Métaboliques. 9(2) : 123-129.
IDF DIABETES ATLAS, Ninth edition 2019/AFRIQUE.
Elisaf MS, Tsatsoulis AA, Katopodis KP, Siamopoulos KC. 1996. Acid-base and electrolyte disturbances in patients with diabetic ketoacidosis. Diabetes Res Clin Pract. 34: 23-27.
Palmer BF, Clegg DJ. 2015. Electrolyte and Acid-Base Disturbances in Patients with Diabetes Mellitus. N Engl J Med.373(6):548-59.
Anago EAA, Medehouenou TCM, Akpovi CD and Tchehouenou H. 2016. Electrolyte disturbances in diabetic patients in Cotonou, Benin. Int J Res Med Sci. 4(12):5430-5435. http://dx.doi.org/10.18203/2320-6012.ijrms20164223.
Hasona NA and Elasbali A. 2016. Evaluation of Electrolytes Imbalance and Dyslipidemia in Diabetic Patients. Med. Sci. 4,7. doi:10.3390/medsci4020007.
Liamis G, Liberopoulos E, Barkas F, Elisaf M. 2014. Diabetes mellitus and electrolyte disorders. World J Clin Cases 2(10): 488-496.
Komjati M, Kastner G, Waldhäusl W, Bratusch-Marrain P. 1988. Detrimental effect of hyperosmolality on insulin-stimulated glucose metabolism in adipose and muscle tissue in vitro. Biochem Med Metab Biol; 39: 312-318.
Liamis G, Milionis H, Elisaf M. Blood pressure drug therapy and electrolyte disturbances. 2008. Int J Clin Pract; 62: 1572-1580. DOI: 10.1111/j.1742-1241.2008.01860.x.
Lindner G and Funk GC. 2013. Hypernatremia in critically ill patients. J Crit Care; 28: 216.e11-216.e20. DOI: 10.1016/j.jcrc.2012.05.001.
Palmer BF. 2004. Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system. N Engl J Med; 351: 585-592. DOI: 10.1056/NEJMra035279.
Shahid SM, Rafique R, Mahboob T. 2005. Electrolytes and sodium transport mechanism in diabetes mellitus. Pak J Pharm Sci.;18(2):6-10.
DeFronzo RA. 1980. Hyperkalemia and hyporeninemic hypoaldo-steronism. Kidney In; 17: 118-134.
Ugwuja E, Eze N. A. 2006. Comparative Study of Serum Electrolytes, Total Protein, Calcium and Phosphate Among Diabetic and HIV/AIDS Patients in Abakaliki, Southeastern, Nigeria. Internet J Lab Med. 2(1).
Sharma A, Hirulkar NB, Ranka P. 2011. Effect of hyperglycemia on electrolytes Imbalance. Int J Pharm Biol Sci Arch.;2(1):526-33.
Steven W and Salyer PA. 2007. Hypochloremia. Essential Emergency Medicine. 2007;311-417. http://dx.doi.org/10.1016/B978-141602971-7.10008-X.
Karuppan A., Sahay M. I., Ravindranaathan R., Haripriyi P., Sriram D. K., George M. 2019. Electrolyte Disturbances among Diabetic Patients Admitted in a Multi-specialty Hospital in Southern India. Journal of Clinical and Diagnostic Research. ; 13(2): OC12-OC15. DOI: 10.7860/JCDR/2019/38487.12573.
DOI: http://dx.doi.org/10.52155/ijpsat.v23.1.2227
Refbacks
- There are currently no refbacks.
Copyright (c) 2020 Togola Issiaka
This work is licensed under a Creative Commons Attribution 4.0 International License.